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Fontan Completion for Younger than 3 Years of Age: Outcome in Patients with Functional Single Ventricle
Laurynas Bezuska1, Virgilijus Lebetkevicius2,3, Kestutis Lankutis3
1Department of Cardiovascular Medicine, Vilnius University, Santariskiu 2, 08661, Vilnius, Lithuania. laurynas.bezuska@santa.lt.
Insights
Performing the Fontan procedure earlier in single ventricle patients may reduce chest drain duration. This study compared outcomes in children under and over 36 months, finding earlier surgery potentially beneficial.
Area of Science:
- Pediatric Cardiac Surgery
- Congenital Heart Disease
- Single Ventricle Physiology
Background:
- The Fontan procedure is a palliative surgery for single ventricle congenital heart defects.
- Optimal timing for Fontan completion after staged palliation remains debated.
- Early Fontan completion is increasingly common but requires careful consideration of outcomes.
Purpose of the Study:
- To evaluate the outcomes of extracardiac total cavopulmonary connection (TCPC) in children undergoing the Fontan procedure at different ages.
- To compare results between patients younger than 36 months (Group A) and those 36 months or older (Group B).
Main Methods:
- Retrospective review of 45 patients with functional single ventricle who underwent extracardiac TCPC between 2000 and 2013.
- Patients were divided into Group A (age < 36 months) and Group B (age ≥ 36 months).
- Data analyzed included hospital stay, intensive care unit stay, mortality, and chest drain duration.
Main Results:
- Overall mortality was low, with no significant difference between groups (p=0.286).
- Group A (younger patients) had a significantly shorter chest drain stay (median 12 days) compared to Group B (median 22 days) (p=0.014).
- Intensive care unit and hospital stay durations showed no significant difference between the groups.
Conclusions:
- Extracardiac TCPC can be performed in younger children (<36 months) with favorable intermediate outcomes.
- Earlier Fontan completion may be associated with reduced chest drain duration, suggesting potential advantages.
- Further research is warranted to confirm long-term benefits of early Fontan completion.
Abstract:
Most single ventricle patients undergo Fontan procedure earlier in current era. However, optimal timing of Fontan completion after an intermediate staging surgery is controversial. We present children who had Fontan surgeries younger than 3 years of age comparing the data with older patients. Between 2000 and 2013, 45 patients with functional single ventricle underwent extracardiac total cavopulmonary connection (TCPC) using GORE-TEX(®) conduit at a single institution. Children were divided into group A (age < 36 months; n = 15) and group B (age ≥ 36 months; n = 30), and retrospectively reviewed. Median follow-up was 2.9 [interquartile range (IQR) 2-4.4] years. There were two hospital deaths and one late death (all in group B, p = 0.286). One TCPC was taken down in group A. The median intensive care unit and hospital stay were 90 (IQR 46-140) h and 21 (IQR 16-33) days for group A versus 65 (IQR 45-115) h and 29 (IQR 20.8-38.5) days for group B, respectively (p = 0.322 and p = 0.057). Ventricular ejection fraction and GORE-TEX(®) conduit size were similar in both groups. The time of chest drain stay was significantly lower in group A (median 12 days, IQR 7-22) than in group B (22 days, IQR 16-32.5) (p = 0.014). Extracardiac TCPC can be performed earlier with good intermediate results. Earlier Fontan procedure might be advantageous for reducing chest drains stay.
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