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Antihypertensive drug prescription pattern before and during pregnancy in France
Veronique Duhalde1, Caroline Delarue1, Isabelle Lacroix1
1Laboratoire de Pharmacologie Médicale et Clinique, Unité de Pharmacoépidémiologie, EA 3696, Université de Toulouse, Faculté de Médecine, 37 allées Jules-Guesde, 31000 Toulouse, France.
Objective:
This study provides firsthand information on antihypertensive prescriptions before and during pregnancy in France.
Methods:
The study, on 23,898 women, was carried out using data from the French Health Insurance System.
Results:
Before and during pregnancy, 1.1% and 5.1% of women received prescriptions for antihypertensive drugs: beta blockers and diuretics before, and nifedipine, nicardipine, labetalol and methyldopa during pregnancy. Sixty-six pregnant women were exposed to angiotensin-converting enzyme inhibitors and angiotensin II receptor antagonists.
Conclusion:
Pregnant women still receive prescriptions for harmful drugs. In order to prevent such exposures, it should be recommended to avoid these prescriptions in women of child-bearing age who plan to be pregnant.
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