Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Hypertension III: Clinical Manifestations and Diagnostic Studies01:30

Hypertension III: Clinical Manifestations and Diagnostic Studies

748
Hypertension is asymptomatic and also referred to as the "silent killer" until it progresses to a severe stage or causes target organ disease. Patients may experience symptoms stemming from the strain on blood vessels and tissues in various organs or the heart's increased workload.Physical exams might show no abnormalities other than high blood pressure. Signs of vascular damage, when present, correspond to the organs supplied by the affected vessels, leading to target organ damage. For...
748
Diabetes Mellitus: Type 2 and Gestational01:22

Diabetes Mellitus: Type 2 and Gestational

5.6K
Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
5.6K
Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches01:23

Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches

557
Biopharmaceutical studies constitute a vital field aiming to enhance drug delivery methods and refine therapeutic approaches, drawing upon diverse interdisciplinary knowledge. In research methodologies, the choice between controlled and non-controlled studies significantly influences the study's reliability and accuracy.
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
557
Pathophysiology of Diabetes01:20

Pathophysiology of Diabetes

4.5K
Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
4.5K
Peritoneal Dialysis II: Peritoneal Dialysis Systems and Complications01:25

Peritoneal Dialysis II: Peritoneal Dialysis Systems and Complications

1.7K
Peritoneal dialysis (PD) is a medical process that removes waste products and excess fluid from the body using the peritoneal membrane as a natural filter.Peritoneal Dialysis MethodsSeveral methods can be used for peritoneal dialysis, including Acute Intermittent Peritoneal Dialysis, Continuous Ambulatory Peritoneal Dialysis, and Automated Peritoneal Dialysis, also known as Continuous Cyclic Peritoneal Dialysis.Acute Intermittent Peritoneal Dialysis (AIPD) is used for patients with uremic...
1.7K
Study Designs in Epidemiology01:20

Study Designs in Epidemiology

1.6K
Epidemiological study designs are fundamental tools for investigating the distribution, determinants, and control of health conditions in populations. They help researchers understand the relationships between exposures and outcomes, and they broadly fall into two categories: "observational" and "experimental" studies.
Observational studies are those where the researcher does not intervene but rather observes natural variations. They include cross-sectional, cohort, and...
1.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Biological markers and metabolic energy indexes of show jumping horses during a field exercise test in Portugal.

Journal of equine veterinary science·2025
Same author

Reply to Correspondence: The Bronchodilator and Anti-Inflammatory Effect of Long-Acting Muscarinic Antagonists in Asthma: An EAACI Position Paper.

Allergy·2025
Same author

The Bronchodilator and Anti-Inflammatory Effect of Long-Acting Muscarinic Antagonists in Asthma: An EAACI Position Paper.

Allergy·2024
Same author

A giant Brunner's gland hamartoma: a rare cause of upper gastrointestinal bleeding.

Acta gastro-enterologica Belgica·2024
Same author

Recurrent cholangitis caused by a giant duodenal diverticulum (Lemmel syndrome) - effective treatment with endoscopic sphincterotomy.

Acta gastro-enterologica Belgica·2024
Same author

Design of a sensor to estimate suspended sediment transport in situ using the measurements of water velocity, suspended sediment concentration and depth.

Journal of environmental management·2024

Related Experiment Video

Updated: Apr 8, 2026

Author Spotlight: Modeling an Aspect of Preeclampsia in Female Mice Using Hypoxic Human Placenta-Derived Small Extracellular Vesicles
05:31

Author Spotlight: Modeling an Aspect of Preeclampsia in Female Mice Using Hypoxic Human Placenta-Derived Small Extracellular Vesicles

Published on: January 26, 2024

1.5K

PP100. Pre-eclampsia: Risk factors and outcomes - A two-year study.

A V Santos1, F Caeiro1, G Dias1

  • 1Obstetrics and Gynecology, Hospital Fernando Fonseca, Varzea de Sintra, Lisbon, Portugal.

Pregnancy Hypertension
|June 25, 2015
PubMed
Summary

Pre-eclampsia (PE) is a serious pregnancy disorder. Key risk factors include prior PE, advanced maternal age, and chronic hypertension, often leading to preterm delivery and maternal complications.

More Related Videos

Human Primary Trophoblast Cell Culture Model to Study the Protective Effects of Melatonin Against Hypoxia/reoxygenation-induced Disruption
12:02

Human Primary Trophoblast Cell Culture Model to Study the Protective Effects of Melatonin Against Hypoxia/reoxygenation-induced Disruption

Published on: July 30, 2016

16.6K
Modeling Encephalopathy of Prematurity Using Prenatal Hypoxia-ischemia with Intra-amniotic Lipopolysaccharide in Rats
07:36

Modeling Encephalopathy of Prematurity Using Prenatal Hypoxia-ischemia with Intra-amniotic Lipopolysaccharide in Rats

Published on: November 20, 2015

12.0K

Related Experiment Videos

Last Updated: Apr 8, 2026

Author Spotlight: Modeling an Aspect of Preeclampsia in Female Mice Using Hypoxic Human Placenta-Derived Small Extracellular Vesicles
05:31

Author Spotlight: Modeling an Aspect of Preeclampsia in Female Mice Using Hypoxic Human Placenta-Derived Small Extracellular Vesicles

Published on: January 26, 2024

1.5K
Human Primary Trophoblast Cell Culture Model to Study the Protective Effects of Melatonin Against Hypoxia/reoxygenation-induced Disruption
12:02

Human Primary Trophoblast Cell Culture Model to Study the Protective Effects of Melatonin Against Hypoxia/reoxygenation-induced Disruption

Published on: July 30, 2016

16.6K
Modeling Encephalopathy of Prematurity Using Prenatal Hypoxia-ischemia with Intra-amniotic Lipopolysaccharide in Rats
07:36

Modeling Encephalopathy of Prematurity Using Prenatal Hypoxia-ischemia with Intra-amniotic Lipopolysaccharide in Rats

Published on: November 20, 2015

12.0K

Area of Science:

  • Obstetrics and Gynecology
  • Maternal-Fetal Medicine
  • Hypertensive Disorders of Pregnancy

Background:

  • Pre-eclampsia (PE) is a significant cause of maternal and fetal morbidity and mortality.
  • Predicting PE remains a clinical challenge despite known risk factors.

Purpose of the Study:

  • To determine the incidence of pre-eclampsia.
  • To identify associated risk factors for PE.
  • To evaluate maternal and fetal outcomes in PE cases.

Main Methods:

  • Retrospective review of clinical records for pregnant women diagnosed with pre-eclampsia.
  • Data collected from January 2008 to December 2009 at Prof. Fernando Fonseca's Hospital.
  • Statistical analysis performed using Excel 2007.

Main Results:

  • PE occurred in 1.1% of pregnant women (90 cases out of 308 hypertensive disorders).
  • Associated risk factors included chronic hypertension (24.4%), maternal age >35 (16.67%), age <20 (14.44%), and prior PE (8.89%).
  • Maternal complications led to ICU admission in 18.89% of cases, including 3.33% with HELLP syndrome; 61.1% experienced preterm delivery.

Conclusions:

  • Pre-eclampsia is a recurrent hypertensive disorder with severe potential, often linked to preterm delivery and significant maternal morbidity.
  • Confirmed adverse outcomes include ICU admissions, HELLP syndrome, and end-organ failure.
  • Identified risk factors reinforce the need for vigilant monitoring and management in high-risk pregnancies.