PP172. Indian scenario of preeclampsia and its consequences and early prophylaxis

M C Jariwala1

  • 1Obstetrics and Gynaecolgy, Jariwala Womens Hospital, Ahmedabad, India.

Insights

Jariwala's therapy shows promise in managing mild to moderate preeclampsia, leading to positive birth outcomes. This approach avoids traditional antihypertensives, potentially improving placental function and reducing complications.

Area of Science:

  • Obstetrics and Gynecology
  • Maternal-Fetal Medicine
  • Perinatology

Background:

  • Preeclampsia is a significant global obstetric challenge, particularly in developing nations.
  • The exact etiology of preeclampsia remains elusive, necessitating novel prevention and treatment strategies.
  • Current understanding of preeclampsia pathogenesis requires further investigation to refine management protocols.

Purpose of the Study:

  • To evaluate the efficacy of Jariwala's therapy for preeclampsia.
  • To explore the etiological factors contributing to preeclampsia development.
  • To establish an improved prophylactic management strategy for preeclampsia.

Main Methods:

  • A cohort of 800 pregnant individuals with preeclampsia was enrolled.
  • Prediction of preeclampsia involved the roll-over test, color Doppler, and monitoring weight gain/edema.
  • Jariwala's protocol was implemented for early intervention to mitigate disease severity.

Main Results:

  • Jariwala's therapy demonstrated effectiveness in mild to moderate preeclampsia cases.
  • 98% of neonates weighed 2kg or more at delivery.
  • 92% of neonates were discharged directly home without complications and exhibited healthy development.

Conclusions:

  • Antihypertensive treatment during pregnancy may lead to intrauterine growth restriction and rebound hypertension.
  • Fetal and placental toxins may increase placental permeability, causing protein loss and multi-system dysfunction.
  • Jariwala's protocol offers an alternative to routine treatment, with pregnancy termination reserved for severe, rapidly progressing cases.
Abstract

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