PP062. Characteristic changes of systemic blood pressure in eclampsia

It was found that eclampsia might be caused by vasogenic edema of brain as the results of breaking autoregulation of cerebral blood flow due to possibly the systemic increase in blood pressure (BP). In the present study, we investigated characteristic changes of systemic BP just after the onset of eclampsia.

Four eclamptic women during pregnancy were participated. Two had labor pains. Two were given anti-hypertensive drugs due to severe hypertension. BP in both systolic and diastolic, and mean arterial pressure (MAP), before and after onset of eclampsia were evaluated.

Basal BP in systolic, diastolic and MAP before eclampsia were 132±13, 79±24, 90±20mmHg. Maximum BP in systolic, diastolic and MAP before eclampsia were 172±10, 96±13 and 121±10mmHg. BP in systolic, diastolic and MAP after eclampsia were 124±23, 74±14 and 91±12mmHg. An increase in MAP was 24±11mmHg before eclampsia, while a decrease was 31±2mmHg after onset of eclampsia.

In eclampsia, an increase in BP was seen just before eclampsia, while a severe decrease in BP (more than 30mmHg of MAP) was seen after it.