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Biosensor-based High Throughput Biopanning and Bioinformatics Analysis Strategy for the Global Validation of Drug-protein Interactions
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Metrabase: a cheminformatics and bioinformatics database for small molecule transporter data analysis and (Q)SAR

Lora Mak1, David Marcus1, Andrew Howlett2

  • 1The Centre for Molecular Informatics, Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW UK ; European Molecular Biology Laboratory - European Bioinformatics Institute (EMBL-EBI), Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SD UK.

Journal of Cheminformatics
|June 25, 2015
PubMed
Summary

Metrabase is a new database integrating human xenobiotic transport and metabolism data. It provides access to over 11,500 interaction records for computational analysis of drug bioavailability and effects.

Keywords:
CYPDatabaseDrug transporterInducerInhibitorMembrane proteinMetabolismMetabolite transporterSubstrateTransport protein

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