Current findings in the pathological evaluation of breast reduction specimens

A study of the histopathologic findings in the specimens of 100 consecutive cases of reduction mammoplasty was performed. The current classification of premalignant breast changes using the presence or absence of atypia in specimens with epithelial hyperplasia was employed. Of the group studied only 1% showed atypical ductal hyperplasia and no cases of lobular carcinoma in situ or ductal carcinoma in situ were found. Fifty percent of the specimens showed simply fibrosis of the stroma dominating the gross and microscopic picture. The other pathological findings in descending order of frequency were cysts (30%) epithelial hyperplasia without atypia (6%), adenosis (5%) and apocrine metaplasia (5%).