Migration of plastic additives from soft polyvinyl chloride bags into normal saline and glucose infusions

Samples of soft polyvinyl chloride (PVC) fluid bags containing normal saline and glucose 50 mg/ml were analyzed for plastic additives. The bags were shaken for 24 hours before analysis. The PVC plastic materials contained di(2-ethylhexyl)phthalate, epoxidized vegetable oils and stearates as the main additives. The same components were found in the solutions. Mono(2-ethylhexyl)phthalate was detected only in the solutions.