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Published on: August 7, 2017
Fast food consumption in pregnancy and subsequent asthma symptoms in young children
O S von Ehrenstein1, H Aralis2, M E S Flores3,4
1Department of Community Health Sciences, Fielding School of Public Health, University of California, Los Angeles, CA, USA.
Insights
Maternal fast food consumption during pregnancy is linked to an increased risk of asthma symptoms in children. Frequent intake by mothers was associated with a higher likelihood of severe asthma in offspring.
Area of Science:
- Environmental Health
- Pediatric Allergy and Immunology
- Nutritional Epidemiology
Background:
- Cross-sectional studies indicate a link between children's fast food intake and asthma/allergy prevalence.
- Maternal diet during pregnancy is a suspected factor influencing offspring's risk for atopic diseases.
Purpose of the Study:
- To investigate the hypothesis that maternal fast food intake during pregnancy elevates the risk of asthmatic symptoms in offspring.
Main Methods:
- A population-based study of 1201 mother/child pairs in Los Angeles.
- Data collected on prenatal fast food intake, diet, lifestyle, and pregnancy factors.
- Asthma and rhinitis symptoms assessed in children at 3.5 years using International Study of Asthma and Allergies in Childhood criteria; Poisson regression used for analysis.
Main Results:
- Maternal prenatal fast food consumption showed a dose-dependent association with increased relative risks for severe, current asthma symptoms.
- Relative risks increased from 0.99 ('once a month') to 4.46 ('every day') compared to 'never' (p for trend = 0.0025).
- A suggestion of increased risks for rhinitis symptoms was also observed.
Conclusions:
- In utero exposure to frequent maternal fast food consumption may represent a significant risk factor for developing asthmatic symptoms in young children.
- Findings highlight the potential impact of prenatal dietary patterns on childhood respiratory health.
Background:
Recent cross-sectional studies suggested children's current fast food consumption to be related to frequency of asthma and allergies. Maternal prenatal diet has been suspected to contribute to children's asthma and atopic disease risks.
Objectives:
We hypothesized that maternal fast food intake during pregnancy increases offspring's risk for asthmatic symptoms.
Methods:
We conducted a population-based study of 1201 mother/child pairs in Los Angeles, California. Detailed information about prenatal fast food intake and other dietary, lifestyle/environmental factors, and pregnancy was collected shortly after birth; further data were retrieved from birth certificates. Using the International Study of Asthma and Allergies in Childhood core questions, asthma and rhinitis symptoms were assessed, and doctor's diagnoses were recorded in offspring 3.5 years after birth. Poisson regression with robust error variance using a log link function was used to estimate relative risks (RRs). Models were adjusted using covariates or propensity scores.
Results:
Maternal prenatal fast food consumption related to increased relative risks of their children for severe, and current asthma symptoms (wheeze last 12 months combined with doctor's diagnosis) in a dose-dependent manner: 'once a month': RR: 0.99 (95% CI: 0.36, 2.75), 'once a week': 1.26 (0.47, 3.34); '3-4 days a week': 2.17 (0.77, 6.12); and 'every day' 4.46 (1.36 14.6) compared to 'never', adjusting for potential confounders (p for trend = 0.0025). There was also suggestion of increased risks for rhinitis symptoms.
Conclusions:
These findings suggest that in utero exposure to frequent fast food through maternal diet may be a risk factor for asthmatic symptoms in young children.
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