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Related Concept Videos

Cytomegalovirus Disease01:27

Cytomegalovirus Disease

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Cytomegalovirus (CMV) disease is caused by human cytomegalovirus, a double-stranded DNA virus of the Herpesviridae family. While primary CMV infection is often asymptomatic in immunocompetent individuals, the virus can cause severe disease in neonates and immunocompromised patients. CMV is the most common cause of congenital viral infection in the United States, and a major pathogen in solid organ and hematopoietic stem cell transplant recipients.CMV is transmitted via bodily fluids, sexual...
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Viral meningitis is the most common form of meningitis and is often referred to as aseptic meningitis to indicate the absence of bacterial involvement. It is generally milder than bacterial meningitis, with symptoms including fever, headache, stiff neck, drowsiness, nausea, photophobia, and vomiting. Rarely, more severe manifestations or death may occur. Common causative agents include enteroviruses, particularly coxsackie A and B viruses and echoviruses, all members of the Enterovirus genus...
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Atypical Pneumonia01:14

Atypical Pneumonia

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Atypical pneumonia, often caused by Mycoplasma pneumoniae, is a form of pulmonary infection that differs from the classical presentation of bacterial pneumonia in both its cause and clinical symptoms. Mycoplasma pneumoniae is a pleomorphic bacterium notable for its lack of a rigid cell wall. This structural characteristic imparts resistance to beta-lactam antibiotics and significantly influences the bacterium’s behavior within the human host.Other pathogens responsible for the disease...
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Peptic Ulcer01:27

Peptic Ulcer

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Peptic ulcers are erosive lesions of the gastric or duodenal lining, most commonly caused by Helicobacter pylori infection. This Gram-negative, helical bacterium has adapted to survive the stomach’s acidic environment by producing urease, which converts urea into ammonia and carbon dioxide. The ammonia neutralizes gastric acid in the bacterium’s immediate environment, allowing colonization of the gastric mucosa. H. pylori attaches to mucus-secreting epithelial cells, penetrates the...
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A Retrospective Study on Endoscopic Surgery for the Treatment of Paravertebral Abscess in Spinal Tuberculosis Patients
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Vertebral Osteomyelitis Caused by Helicobacter cinaedi.

Aisa Yoshizaki1, Hiroshi Takegawa2, Asako Doi3

  • 1Department of General Internal Medicine, Kobe City Medical Center General Hospital, Kobe, Japan.

Journal of Clinical Microbiology
|June 26, 2015
PubMed
Summary

Helicobacter cinaedi can cause serious infections. This report details the first known case of vertebral osteomyelitis due to H. cinaedi in an elderly patient, successfully treated with doxycycline.

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Area of Science:

  • Infectious Diseases
  • Microbiology
  • Orthopedics

Background:

  • Helicobacter cinaedi is a known pathogen causing various infections, including bacteremia, cellulitis, and gastroenteritis.
  • Vertebral osteomyelitis is a serious bone infection, often presenting with back pain and fever, requiring prompt diagnosis and treatment.

Observation:

  • A case of vertebral osteomyelitis caused by Helicobacter cinaedi in an elderly male patient is presented.
  • The patient exhibited symptoms of low back pain and fever, indicative of a potential spinal infection.

Findings:

  • Helicobacter cinaedi was identified as the causative agent in both the bloodstream and the infected lumbar disc.
  • The patient's infection was successfully treated with a course of oral doxycycline over 11 weeks.

Implications:

  • This case expands the spectrum of clinical manifestations associated with Helicobacter cinaedi infections.
  • Highlights the importance of considering H. cinaedi in the differential diagnosis of vertebral osteomyelitis, especially in elderly patients with relevant symptoms.
  • Demonstrates the efficacy of oral doxycycline in treating H. cinaedi-induced vertebral osteomyelitis.