Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Genome-wide Association Studies-GWAS01:11

Genome-wide Association Studies-GWAS

16.8K
Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
GWAS does not require the identification of the target gene involved in...
16.8K
Genomics02:02

Genomics

41.8K
Genomics is the science of genomes: it is the study of all the genetic material of an organism. In humans, the genome consists of information carried in 23 pairs of chromosomes in the nucleus, as well as mitochondrial DNA. In genomics, both coding and non-coding DNA is sequenced and analyzed. Genomics allows a better understanding of all living things, their evolution, and their diversity. It has a myriad of uses: for example, to build phylogenetic trees, to improve productivity and...
41.8K
Genome Annotation and Assembly03:36

Genome Annotation and Assembly

22.2K
The genome refers to all of the genetic material in an organism. It can range from a few million base pairs in microbial cells to several billion base pairs in many eukaryotic organisms. Genome assembly refers to the process of taking the DNA sequencing data and putting it all back together in a correct order to create a close representation of the original genome. This is followed by the identification of functional elements on the newly assembled genome, a process called genome annotation.
22.2K
Genomic DNA in Eukaryotes00:58

Genomic DNA in Eukaryotes

54.3K
Eukaryotes have large genomes compared to prokaryotes. To fit their genomes into a cell, eukaryotic DNA is packaged extraordinarily tightly inside the nucleus. To achieve this, DNA is tightly wound around proteins called histones, which are packaged into nucleosomes that are joined by linker DNA and coil into chromatin fibers. Additional fibrous proteins further compact the chromatin, which is recognizable as chromosomes during certain phases of cell division.
54.3K
Evolutionary Relationships through Genome Comparisons02:54

Evolutionary Relationships through Genome Comparisons

7.3K
Genome comparison is one of the excellent ways to interpret the evolutionary relationships between organisms. The basic principle of genome comparison is that if two species share a common feature, it is likely encoded by the DNA sequence conserved between both species. The advent of genome sequencing technologies in the late 20th century enabled scientists to understand the concept of conservation of domains between species and helped them to deduce evolutionary relationships across diverse...
7.3K
Genome Size and the Evolution of New Genes03:21

Genome Size and the Evolution of New Genes

3.7K
3.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Hepatic Bmal1 alleviates cholestasis in female mice through direct regulation of SULT2A1.

Biochemical pharmacology·2026
Same author

Artificial Intelligence for Evidence Synthesis of Emerging Biologics to Improve Skeletal Health in Osteogenesis Imperfecta: Systematic Review and Meta-Analysis.

Journal of medical Internet research·2026
Same author

"Beyond the state: First-person ethics and the governance of targeted therapies in China".

Social science & medicine (1982)·2026
Same author

The Effect of Thermal Pain on Working Memory: Behavioral Evidence from the n-Back Task.

Behavioral sciences (Basel, Switzerland)·2026
Same author

TRAPing trigeminal ganglion neurons driving mechanical allodynia.

Trends in neurosciences·2026
Same author

Lenvatinib triggers an EGR1-ZNF768-SLC7A11 adaptive response to limit ferroptosis-mediated therapeutic efficacy in hepatocellular carcinoma.

Cancer biology & medicine·2026

Related Experiment Video

Updated: Apr 8, 2026

Comprehensive Workflow for the Genome-wide Identification and Expression Meta-analysis of the ATL E3 Ubiquitin Ligase Gene Family in Grapevine
10:40

Comprehensive Workflow for the Genome-wide Identification and Expression Meta-analysis of the ATL E3 Ubiquitin Ligase Gene Family in Grapevine

Published on: December 22, 2017

11.1K

BGD: a database of bat genomes.

Jianfei Fang1, Xuan Wang1, Shuo Mu1

  • 1Institute of Molecular Ecology and Evolution, SKLEC & IECR, East China Normal University, Shanghai, China.

Plos One
|June 26, 2015
PubMed
Summary

Researchers created the Bat Genome Database (BGD), a unified resource for bat genome and gene data. This accessible portal aids understanding of bat evolution and sequence analysis.

Area of Science:

  • Genomics
  • Evolutionary Biology
  • Bioinformatics

Background:

  • Bats represent ~20% of mammalian species and are unique for powered flight.
  • Specialized traits drive research into bat evolution, but a unified genomic resource is lacking.

Purpose of the Study:

  • To establish a comprehensive, accessible database for annotated bat genomes and genes.
  • To facilitate comparative genomics and evolutionary studies in bats.

Main Methods:

  • Integrated genomic data from six bat species (two megabats, four microbats).
  • Developed a web portal with gene annotation querying and browsable genome tracks.
  • Incorporated an online phylogenetic analysis tool for gene studies.

Main Results:

More Related Videos

Navigating MARRVEL, a Web-Based Tool that Integrates Human Genomics and Model Organism Genetics Information
09:37

Navigating MARRVEL, a Web-Based Tool that Integrates Human Genomics and Model Organism Genetics Information

Published on: August 15, 2019

10.6K
Determining the Likelihood of Variant Pathogenicity Using Amino Acid-level Signal-to-Noise Analysis of Genetic Variation
07:15

Determining the Likelihood of Variant Pathogenicity Using Amino Acid-level Signal-to-Noise Analysis of Genetic Variation

Published on: January 16, 2019

11.5K

Related Experiment Videos

Last Updated: Apr 8, 2026

Comprehensive Workflow for the Genome-wide Identification and Expression Meta-analysis of the ATL E3 Ubiquitin Ligase Gene Family in Grapevine
10:40

Comprehensive Workflow for the Genome-wide Identification and Expression Meta-analysis of the ATL E3 Ubiquitin Ligase Gene Family in Grapevine

Published on: December 22, 2017

11.1K
Navigating MARRVEL, a Web-Based Tool that Integrates Human Genomics and Model Organism Genetics Information
09:37

Navigating MARRVEL, a Web-Based Tool that Integrates Human Genomics and Model Organism Genetics Information

Published on: August 15, 2019

10.6K
Determining the Likelihood of Variant Pathogenicity Using Amino Acid-level Signal-to-Noise Analysis of Genetic Variation
07:15

Determining the Likelihood of Variant Pathogenicity Using Amino Acid-level Signal-to-Noise Analysis of Genetic Variation

Published on: January 16, 2019

11.5K
  • Launched the Bat Genome Database (BGD), the first of its kind for bats.
  • BGD provides access to integrated genomic data and analysis tools.
  • The database supports efficient searching and browsing of bat genomic information.

Conclusions:

  • BGD serves as a crucial, centralized resource for bat genomic research.
  • The database will advance the understanding of bat evolution and genomic analysis.
  • BGD is freely available to the biological community for research and discovery.