Experience of influenza A H1N1 in a paediatric emergency unit

Suat Biçer1, Hülya Ercan Sariçoban1, Ahmet Oğuzhan Özen1

  • 1Department of Child Health and Pediatrics, Faculty of Medicine, Yeditepe University; Department of Medical Microbiology, Faculty of Medicine, Yeditepe University, Istanbul, Turkey.

Insights

Influenza A (H1N1) infection in 2009 was associated with higher fever and myalgia. Patients with H1N1 also showed significantly lower lymphocyte counts compared to those without the virus.

Area of Science:

  • Infectious Diseases
  • Virology
  • Public Health

Background:

  • Influenza A (H1N1) emerged as a significant public health concern during the 2009 influenza season.
  • Understanding the clinical spectrum and diagnostic markers of H1N1 is crucial for effective patient management.

Purpose of the Study:

  • To evaluate the symptoms, clinical findings, treatment, and complications of H1N1 influenza in emergency unit patients.
  • To compare clinical and laboratory findings between patients with and without H1N1 infection.

Main Methods:

  • Retrospective evaluation of clinical and laboratory findings of pediatric patients during the 2009 influenza season.
  • Diagnosis confirmed by polymerase chain reaction and/or rapid antigen testing.
  • Comparison of H1N1-positive (Group I) and H1N1-negative (Group II) patient cohorts.

Main Results:

  • H1N1 patients (Group I) exhibited higher fever (mean 39.0°C) and a higher incidence of myalgia compared to Group II.
  • Lymphopenia was significantly more prevalent in Group I (81.8%) than in Group II (23.5%).
  • Diarrhea was observed in two H1N1 patients without significant respiratory symptoms.

Conclusions:

  • Fever and myalgia are key indicators differentiating H1N1 influenza.
  • Lymphopenia serves as a significant laboratory marker for H1N1 infection.
  • While most cases were managed outpatient, some required hospitalization and oseltamivir treatment.

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