Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Proteomics01:33

Proteomics

10.2K
A proteome is the entire set of proteins that a cell type produces. We can study proteomes using the knowledge of genomes because genes code for mRNAs, and the mRNAs encode proteins. Although mRNA analysis is a step in the right direction, not all mRNAs are translated into proteins.
Proteomics is the study of proteomes' function. It involves the large-scale systematic study of the proteome to denote the protein complement expressed by a genome. Scientist Mark Wilkins coined the term...
10.2K
Applications of Molecular Taxonomy01:20

Applications of Molecular Taxonomy

665
Molecular taxonomy has revolutionized the understanding and classification of bacteria, providing precise insights into their diversity, evolutionary relationships, and ecological roles. By utilizing molecular techniques such as DNA sequencing and fingerprinting, researchers have made significant strides in various fields related to bacterial studies.Resolving Taxonomic AmbiguitiesMolecular taxonomy has been instrumental in distinguishing closely related bacterial species initially thought to...
665
Genomics02:02

Genomics

41.8K
Genomics is the science of genomes: it is the study of all the genetic material of an organism. In humans, the genome consists of information carried in 23 pairs of chromosomes in the nucleus, as well as mitochondrial DNA. In genomics, both coding and non-coding DNA is sequenced and analyzed. Genomics allows a better understanding of all living things, their evolution, and their diversity. It has a myriad of uses: for example, to build phylogenetic trees, to improve productivity and...
41.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Cancer-related micropeptides encoded by ncRNAs: Promising drug targets and prognostic biomarkers.

Cancer letters·2022
Same author

Mutagenesis of bracelet cyclotide hyen D reveals functionally and structurally critical residues for membrane binding and cytotoxicity.

The Journal of biological chemistry·2022
Same author

Cystine Knot Peptides with Tuneable Activity and Mechanism.

Angewandte Chemie (International ed. in English)·2022
Same author

Protocols for measuring the stability and cytotoxicity of cyclotides.

Methods in enzymology·2022
Same author

Phage display-based discovery of cyclic peptides against the broad spectrum bacterial anti-virulence target CsrA.

European journal of medicinal chemistry·2022
Same author

Towards a generic prototyping approach for therapeutically-relevant peptides and proteins in a cell-free translation system.

Nature communications·2022
Same journal

Chemical, Biological, and Ecological Evidence for Aerobic Deoxynivalenol Detoxification in Agronomic Soil-Derived Bacterial Communities.

Toxins·2026
Same journal

Botulinum Toxin Treatment for Uncommon Phenotypes of Laryngeal Adductor Breathing Dystonia.

Toxins·2026
Same journal

Enhancing Neuronal Networks with <i>Rhinella schneideri</i> Skin Secretion Molecules: Implications for Neurodegenerative Disorders.

Toxins·2026
Same journal

Dangerous Measures: A Case Report and Review of Motoro Ray Envenomation.

Toxins·2026
Same journal

The Impact of OnabotulinumtoxinA on Oral Pain Medication Prescription Fills and Low-Value Care in Patients with Cervical Dystonia in the United States: A Retrospective Claims Analysis.

Toxins·2026
Same journal

Broad-Spectrum Antiviral and Antibacterial Activity of the Scorpion Venom Peptide HP1090.

Toxins·2026
See all related articles

Related Experiment Video

Updated: Apr 8, 2026

High Throughput Quantitative Expression Screening and Purification Applied to Recombinant Disulfide-rich Venom Proteins Produced in E. coli
12:16

High Throughput Quantitative Expression Screening and Purification Applied to Recombinant Disulfide-rich Venom Proteins Produced in E. coli

Published on: July 30, 2014

25.0K

Bioinformatics-Aided Venomics.

Quentin Kaas1, David J Craik2

  • 1Institute for Molecular Bioscience, the University of Queensland, Brisbane, QLD 4072, Australia. q.kaas@imb.uq.edu.au.

Toxins
|June 26, 2015
PubMed
Summary
This summary is machine-generated.

Venomics integrates transcriptomics and proteomics to analyze venom toxins. Computational tools are crucial for classifying data and discovering toxin sequences, structures, and functions, despite challenges like sequence divergence and modifications.

Keywords:
algorithmsdatabasesmolecular modelingphylogenyproteomicstoxinstranscriptomics

More Related Videos

In Vivo Functional Study of Disease-associated Rare Human Variants Using Drosophila
06:41

In Vivo Functional Study of Disease-associated Rare Human Variants Using Drosophila

Published on: August 20, 2019

14.5K
Author Spotlight: Emerging Technologies and Advanced Tools for Decoding Metabolomics Data Analysis
07:11

Author Spotlight: Emerging Technologies and Advanced Tools for Decoding Metabolomics Data Analysis

Published on: November 10, 2023

3.5K

Related Experiment Videos

Last Updated: Apr 8, 2026

High Throughput Quantitative Expression Screening and Purification Applied to Recombinant Disulfide-rich Venom Proteins Produced in E. coli
12:16

High Throughput Quantitative Expression Screening and Purification Applied to Recombinant Disulfide-rich Venom Proteins Produced in E. coli

Published on: July 30, 2014

25.0K
In Vivo Functional Study of Disease-associated Rare Human Variants Using Drosophila
06:41

In Vivo Functional Study of Disease-associated Rare Human Variants Using Drosophila

Published on: August 20, 2019

14.5K
Author Spotlight: Emerging Technologies and Advanced Tools for Decoding Metabolomics Data Analysis
07:11

Author Spotlight: Emerging Technologies and Advanced Tools for Decoding Metabolomics Data Analysis

Published on: November 10, 2023

3.5K

Area of Science:

  • Biochemistry
  • Bioinformatics
  • Genomics

Background:

  • Venomics combines transcriptomics and proteomics to study venom composition.
  • Toxins present significant challenges in sequence identification and functional analysis due to divergence and modifications.

Purpose of the Study:

  • To review computational approaches for classifying and analyzing venomics data.
  • To highlight bioinformatics algorithms for toxin sequence, structure, and function discovery.
  • To discuss challenges and future directions in venomics research.

Main Methods:

  • Review of computational and bioinformatics tools for venomics data analysis.
  • Exploration of algorithms for identifying toxin nucleic acid and protein sequences.
  • Discussion of methods for predicting toxin structures, functions, and evolutionary relationships.

Main Results:

  • Bioinformatics is essential for overcoming challenges in toxin identification and annotation.
  • Toxin sequence identification requires advanced algorithms beyond basic similarity searches.
  • Predicting mature toxin regions and evolutionary links are key areas of focus.

Conclusions:

  • Computational approaches are vital for advancing venomics research.
  • Overcoming challenges in toxin analysis will accelerate venom toxin discovery.
  • Future bioinformatics and modeling may enable accurate prediction of toxin activity and specificity.