Leukemia diagnosis: today and tomorrow.

Area of Science:

• Hematology
• Oncology
• Diagnostic Technologies

Background:

• The European LeukemiaNet (ELN) comprises work packages focused on leukemia diagnosis.
• Four ELN work packages convened in 2015 to discuss diagnostic advancements.

Purpose of the Study:

• To collectively examine the current status and future prospects of key leukemia diagnostic techniques.
• To summarize the outcomes of discussions on cytomorphology, flow cytometry, cytogenetics, next-generation sequencing, and minimal residual disease detection.

Main Methods:

• Review of current diagnostic techniques in leukemia.
• Discussion of future trends in leukemia diagnostics.
• Compendium of findings from ELN work packages.

Main Results:

• Evaluation of cytomorphology, flow cytometry, cytogenetics, and next-generation sequencing in leukemia diagnosis.
• Assessment of minimal residual disease detection methods for leukemia follow-up.
• Identification of areas for improvement and future research in leukemia diagnostics.

Conclusions:

• The ELN meeting provided a comprehensive overview of leukemia diagnostic modalities.
• The findings highlight the evolving landscape of leukemia diagnosis and follow-up.
• This compendium serves as a guide to current and future diagnostic strategies in leukemia.