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Related Concept Videos

Gastrointestinal Motility Disorders01:20

Gastrointestinal Motility Disorders

Gastrointestinal or GI motility disorders are characterized by irregular gastrointestinal tract movements, disrupting food transit from the mouth to the anus. They are caused by damage or dysfunction in gut muscles or nerves. These disorders can cause symptoms such as severe constipation, diarrhea, abdominal pain, and swallowing difficulties. Disorders can affect any segment of the GI tract and range widely in severity, from common conditions like GERD to life-threatening conditions like...
Diseases of the Liver and Gallbladder01:26

Diseases of the Liver and Gallbladder

Liver and gallbladder diseases are a significant health concern, with prominent conditions including cirrhosis, hepatitis, non-alcoholic fatty liver disease (NAFLD), and gallstones. Jaundice is a common manifestation of liver and biliary disease.
Cirrhosis is characterized by the scarring of hepatic lobules in the liver, which are replaced by fibrous tissue, affecting the liver's normal functioning. NAFLD, on the other hand, is caused by an excessive build-up of fat in the liver, not related to...
Anatomy of the Gastrointestinal System01:26

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Gastroesophageal Reflux Disease II: Clinical Features and Management01:29

Gastroesophageal Reflux Disease II: Clinical Features and Management

Gastroesophageal reflux disease, or GERD, is a persistent medical condition that affects many individuals worldwide. Its clinical manifestations can vary greatly, making diagnosis and management challenging for healthcare professionals. The following is a comprehensive overview of the clinical manifestations, assessment, and management strategies for GERD.
Clinical Manifestations
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Gastritis-I: Introduction and Types01:27

Gastritis-I: Introduction and Types

Gastritis, defined by the inflammation or irritation of the stomach lining or gastric mucosa, manifests in several distinct forms: acute, chronic, reactive, and a specific subtype known as autoimmune metaplastic atrophic gastritis.
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Gastroesophageal Reflux Disease01:25

Gastroesophageal Reflux Disease

Gastroesophageal reflux disease (GERD) is the backward flow of stomach contents (acid, pepsin, or bile) into the esophagus, causing mucosal inflammation known as esophagitis. It results from failure of antireflux mechanisms, mainly the lower esophageal sphincter (LES), influenced by mechanical and physiological factors.Etiology and Risk FactorsGERD develops when LES function is weakened or when intra-abdominal pressure increases. Risk factors include aging, obesity, and sliding hiatal hernia,...

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Tissue Engineering of the Intestine in a Murine Model
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Gastroenterology: the first 40 years.

R H Salter, K M Holmes

    The British Journal of Clinical Practice
    |November 1, 1989
    PubMed
    Summary

    Functional gastrointestinal disorders are common in younger patients (under 40) referred to gastroenterology clinics. Peptic ulceration and reflux were the most frequent organic diagnoses, with malignancy being rare.

    Area of Science:

    • Gastroenterology
    • Internal Medicine
    • Clinical Diagnostics

    Background:

    • Functional gastrointestinal disorders (FGIDs) represent a significant patient load in gastroenterology.
    • Understanding the prevalence of FGIDs and organic disorders in younger demographics is crucial for appropriate healthcare resource allocation.

    Purpose of the Study:

    • To determine the prevalence of functional gastrointestinal disorders in patients aged 40 and under referred to a district general hospital gastroenterology clinic.
    • To identify the common organic gastrointestinal disorders within this specific age group.

    Main Methods:

    • Retrospective analysis of patient referrals to a combined gastroenterology clinic.
    • Diagnosis based on established clinical criteria for functional and organic gastrointestinal disorders.

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    Main Results:

    • Over 50% of patients aged 40 and under were diagnosed with functional gastrointestinal disorders.
    • Peptic ulceration, gastro-oesophageal reflux, biliary tract disease, and inflammatory bowel disease constituted nearly 70% of organic diagnoses.
    • Malignant diseases were infrequently encountered in this cohort.

    Conclusions:

    • Functional gastrointestinal disorders are highly prevalent in younger adult patients presenting to gastroenterology services.
    • Diagnostic strategies should consider the high likelihood of FGIDs and common organic conditions like peptic ulceration and reflux in this demographic.
    • The low incidence of malignancy suggests a need for judicious use of invasive investigations in younger patients presenting with gastrointestinal symptoms.