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Imported case of MERS-CoV infection identified in China, May 2015: detection and lesson learned

J Wu1, L Yi, L Zou

  • 1Medical Key Laboratory for Repository and Application of Pathogenic Microbiology, Research Center for Pathogens Detection Technology of Emerging Infectious Diseases, Guangdong Provincial Center for Disease Control and Prevention, Guangzhou, China.

Euro Surveillance : Bulletin Europeen Sur Les Maladies Transmissibles = European Communicable Disease Bulletin
|June 26, 2015
PubMed

Insights

An imported Middle East respiratory syndrome coronavirus (MERS-CoV) case was confirmed in China in May 2015. Extensive contact tracing found no secondary MERS-CoV infections among 78 close contacts after 14 days of monitoring.

Area of Science:

  • Infectious Diseases
  • Public Health
  • Virology

Background:

  • Middle East respiratory syndrome coronavirus (MERS-CoV) is a significant global health concern.
  • The first imported MERS-CoV case in China presented a potential risk for local transmission.

Purpose of the Study:

  • To report preliminary findings of the first imported MERS-CoV case in China.
  • To assess the risk of MERS-CoV transmission through comprehensive contact tracing.

Main Methods:

  • Case investigation and clinical monitoring of the index patient.
  • Identification and quarantine of 78 close contacts.
  • 14-day follow-up and diagnostic testing for MERS-CoV in all contacts.

Main Results:

  • The index patient was confirmed with MERS-CoV infection and remained under treatment.
  • None of the 78 identified close contacts developed MERS-CoV symptoms.
  • All close contacts tested negative for MERS-CoV after the 14-day monitoring period.

Conclusions:

  • The initial imported MERS-CoV case in China did not lead to secondary transmission among identified close contacts.
  • Effective contact tracing and isolation measures appear crucial in controlling MERS-CoV outbreaks.
  • Further surveillance is necessary to understand MERS-CoV epidemiology in China.

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