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L1CAM in human cancer.

Peter Altevogt1, Kai Doberstein2, Mina Fogel3

  • 1Skin Cancer Unit, German Cancer Research Center (DKFZ), Heidelberg, Germany and Department of Dermatology, Venereology and Allergology, University Medical Center Mannheim, Ruprecht-Karl University of Heidelberg, Mannheim, Germany.

International Journal of Cancer
|June 27, 2015
PubMed
Summary

L1 cell adhesion molecule (L1CAM), initially key in neural development, is now recognized as a tumor antigen. Its expression in cancers correlates with poor prognosis, making it a target for diagnostics and therapies.

Keywords:
L1CAMimmunohistochemistrytherapy modeltumor therapy

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