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Updated: Apr 8, 2026
Vascularized Composite Upper Limb Allograft Harvesting for Proximal Arm Allotransplantation
Published on: June 13, 2025
Does pectoralis major flap harvesting induce upper extremity dysfunction?
Qiang Sun1, Shu Guo2, Di Wang1
1Department of Plastic Surgery, The First Affiliated Hospital of China Medical University, Shenyang, China.
Objective:
To evaluate the effect of pectoralis major myocutaneous (PMM) flap reconstruction on upper extremity dysfunction.
Methods:
Patients undergoing PMM flap reconstruction following head and neck cancer resection were enrolled. The control group comprised age-, sex- and clinical characteristic-matched patients undergoing non-PMM flap reconstruction. All patients completed the Disability of the Arm, Shoulder, and Hand (DASH) questionnaire preoperatively and >1 year postoperatively.
Results:
There was no significant difference between pre- and postoperative DASH scores in the control group (n = 46; 2.38 ± 3.33 and 2.99 ± 4.21, respectively). In the PMM flap group (n = 46), the postoperative DASH score was significantly higher than the preoperative score (7.00 ± 9.13 and 2.44 ± 3.50, respectively). In the PMM flap group, flap size was significantly associated with postoperative DASH score.
Conclusion:
PMM flap reconstruction has a small but significant negative effect on upper extremity dysfunction.
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