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Implantation of Left Ventricular Assist Device (LVAD) in Juvenile Landrace Swine: A LVAD Implantation Model of Pediatric Heart Failure
Published on: January 16, 2026
Reasons Why Eligible Candidates Decline Left Ventricular Assist Device Placement
Courtenay R Bruce1, Kristin M Kostick2, Estevan D Delgado2
1Center for Medical Ethics and Health Policy, Baylor College of Medicine, Houston, Texas; Bioethics Program, Houston Methodist Hospital, Houston, Texas.
Understanding patient refusal of left ventricular assist device (LVAD) placement is crucial. Some patients initially refuse LVAD, but change their minds as symptoms worsen, citing concerns about mobility and transplant eligibility.
Area of Science:
- Cardiology
- Medical Ethics
- Patient Decision-Making
Background:
- Understanding patient beliefs and perceptions is vital for informed consent regarding left ventricular assist device (LVAD) placement.
- Investigating factors influencing LVAD placement refusal and decision changes is essential for improving patient care.
Purpose of the Study:
- To explore the factors influencing patient decisions to refuse left ventricular assist device (LVAD) implantation.
- To analyze the evolving decision-making process of patients who initially decline LVAD but later accept it.
Main Methods:
- Conducted structured interviews with 21 patients who declined LVAD placement.
- Analyzed interview transcripts quantitatively using Atlas.ti software.
- Included both prospectively and retrospectively identified LVAD decliners.
Main Results:
- Eleven patients persistently declined LVAD, while ten initially refused but later accepted the device.
- Decision changes were often prompted by worsening symptoms.
- Key concerns included impact on mobility, distrust of technology, perceived impact on transplant eligibility, and feeling "not sick enough".
Conclusions:
- Patient perspectives are critical for refining informed consent and refusal processes for LVAD implantation.
- Decision-making regarding LVAD placement is dynamic and influenced by evolving symptoms and specific patient concerns.
- Clinical recommendations can be developed to address patient beliefs and improve the LVAD decision-making pathway.
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