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Brain metastasis research: a late awakening

Matthias Preusser¹, Michael Weller²

¹Department of Medicine I, Comprehensive Cancer Center-CNS Unit, Medical University of Vienna, Waehringer Guertel 18-20, 1090 Vienna, Austria. matthias.preusser@meduniwien.ac.at.

Chinese Clinical Oncology

|June 27, 2015

Summary

No abstract available in PubMed .

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Metastasis

Metastasis

Metastasis is the spread of cancer cells from the original site to distant locations in the body. Cancer cells can spread via blood vessels (hematogenous) as well as lymph vessels in the body.
Epithelial-to-Mesenchymal Transition
The epithelial-to-mesenchymal transition or EMT is a developmental process commonly observed in wound healing, embryogenesis, and cancer metastasis. EMT is induced by transforming growth factor-beta (TGF-β) or receptor tyrosine kinase (RTK) ligands, which further...

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