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Updated: Apr 8, 2026

Cerenkov Luminescence Imaging CLI for Cancer Therapy Monitoring
Published on: November 13, 2012
Unified approach for bioluminescence, Cerenkov, β, X and γ rays imaging
Antonello E Spinelli1, Carmen R Gigliotti1, Federico Boschi2
1Medical Physics Department and Centre for Experimental Imaging, San Raffaele Scientific Institute, Via Olgettina 60, 20132 Milan, Italy.
Abstract:
The goal of this work is to demonstrate that a CCD-based system can be used as a unified device which allows visible, β, X and γ rays imaging. A system composed of a CCD coupled with lens mounted on a black light-tight box and a high resolution intensifying screen for the radiations conversion were used. In order to investigate the detection of different type of radiations in vitro and in vivo experiments were performed. The comparison of the results obtained with our prototype and those obtained with dedicated commercial devices showed a good agreement.
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