Interference control training for PTSD: A randomized controlled trial of a novel computer-based intervention.

Area of Science:

• Psychology
• Neuroscience
• Cognitive Science

Background:

• Post-traumatic stress disorder (PTSD) is a chronic condition with debilitating intrusive memories.
• Existing PTSD treatments are effective, but alternative interventions are needed.
• Impaired proactive interference control may contribute to PTSD re-experiencing symptoms, suggesting a potential therapeutic target.

Purpose of the Study:

• To test a novel computerized cognitive training intervention designed to improve proactive interference control in women with PTSD.
• To assess the impact of this cognitive training on PTSD symptoms and cognitive performance.

Main Methods:

• Forty-two women diagnosed with PTSD were recruited.
• Participants were randomly assigned to either a computerized cognitive training group or a control group.
• Cognitive performance and PTSD symptom severity were assessed before and after the intervention.

Main Results:

• The cognitive training group showed significantly greater improvements in PTSD re-experiencing symptoms compared to the control group.
• Individuals in the training group also demonstrated significant improvements in proactive interference control performance.
• General distress and other PTSD symptoms improved similarly in both groups over time.

Conclusions:

• Computerized cognitive training aimed at enhancing proactive interference control may be a promising novel intervention for PTSD.
• Further research is needed to elucidate the mechanisms of action and broader implications for PTSD treatment models.