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Incidence of HIV Infection in Young Gay, Bisexual, and Other YMSM: The P18 Cohort Study
Perry Halkitis1, Farzana Kapadia, Danielle Ompad
1Center for Health, Identity, Behavior and Prevention Studies, The Steinhardt School of Culture, Education, and Human Development, New York University, New York, NY.
Content:
HIV infections continue to rise in a new generation of young gay, bisexual, and other young men who have sex with men (YMSM) despite 3 decades of HIV prevention and recent biomedical technologies to deter infection.
Objectives:
To examine the incidence of HIV and the demographic, behavioral, and structural factors associated with incident infections.
Design:
A prospective cohort study.
Participants:
Six hundred YMSM who were aged 18-19 years at baseline.
Results:
At baseline, 6 prevalent cases of HIV were detected. Over the course of 36 months and 6 additional waves of data collection, we identified 43 (7.2%) incident cases of HIV. Incident infections were marginally higher among those residing in neighborhoods with higher rates of HIV prevalence. Using Cox proportional hazards models, we detected that hazard ratios (HRs) for time to HIV seroconversion were significantly higher for black YMSM (HR = 7.46) and mixed/other race YMSM (HR = 7.99), and older age at sexual debut with another man was associated with a lower risk of HIV seroconversion (HR = 0.50), whereas low perceived familial socioeconomic status was marginally associated with an increased risk for HIV seroconversion (HR = 2.45).
Conclusions:
These findings support the disparities for HIV that exist within the population of sexual minority men and suggest that we attend to behavioral, structural, and social conditions to effectively tailor HIV prevention for a new generation of YMSM with keen eyes to the conditions faced by racial and ethnic minority YMSM, which heightened their risk for acquiring HIV.
Insights
HIV infections are rising among young men who have sex with men (YMSM). Black and mixed-race YMSM face significantly higher risks, highlighting the need for tailored prevention strategies.
Area of Science:
- Public Health
- Epidemiology
- Social Sciences
Background:
- HIV infections continue to increase among young gay, bisexual, and other men who have sex with men (YMSM).
- Existing prevention methods and biomedical technologies have not fully curbed the rise in new infections within this demographic.
Purpose of the Study:
- To investigate the incidence of Human Immunodeficiency Virus (HIV).
- To identify demographic, behavioral, and structural factors associated with new HIV infections in young YMSM.
Main Methods:
- A prospective cohort study design was employed.
- Six hundred YMSM, aged 18-19 years at the study's commencement, were followed.
- Data were collected over 36 months across six waves.
Main Results:
- The study detected 43 (7.2%) incident HIV cases over 36 months.
- Higher HIV prevalence in neighborhoods correlated with increased incident infections.
- Significant risk factors included Black (HR=7.46) and mixed/other race (HR=7.99) YMSM, with older age at sexual debut (HR=0.50) showing a protective effect. Low perceived familial socioeconomic status was marginally associated with increased risk (HR=2.45).
Conclusions:
- Findings underscore existing HIV disparities among sexual minority men.
- Effective HIV prevention for young YMSM requires addressing behavioral, structural, and social determinants.
- Particular attention must be paid to racial and ethnic minority YMSM due to heightened acquisition risks.
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