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Experimental left pneumonectomy in pigs: procedure and management
Antonello Bufalari1, Valentina De Monte1, Roberta Pecoriello2
1Department of Veterinary Medicine, University of Perugia, Perugia, Italy.
The Journal of Surgical Research
|June 28, 2015
Summary
This study outlines effective procedures for left pneumonectomy in swine, detailing surgical steps, anesthesia, and postoperative care to improve research efficiency and reduce costs.
Area of Science:
- Veterinary Surgery
- Animal Models
- Thoracic Surgery
Background:
- Limited detailed protocols exist for major pulmonary resections in swine.
- Standardized perioperative management is crucial for successful swine models.
Purpose of the Study:
- To describe an effective methodology for left pneumonectomy in swine.
- To optimize resources and improve research outcomes using swine models.
Main Methods:
- Retrospective analysis of 11 left pneumonectomies.
- Systematic evaluation of animal data, operative reports, anesthesia records, and perioperative care.
- Assessment of care-taking, therapy administration, and stabling.
Main Results:
- Median surgery time: 2 hours 16 minutes with a core team of 2 operators and 1 anesthesiologist.
- Key surgical steps include careful dissection of pulmonary ligament, veins, artery, and bronchus.
- Effective anesthesia management involves preoxygenation, high respiratory rates with low tidal volume, and noninvasive ventilation post-extubation.
Conclusions:
- Standardized methodology reduces surgical time, stress, and cost.
- Improved efficiency enhances the quality and quantity of research utilizing swine models.
- Animal-friendly postoperative care is essential for successful recovery.
