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Updated: Apr 8, 2026

Optimization of the Retinal Vein Occlusion Mouse Model to Limit Variability
Published on: August 6, 2021
Central retinal vein occlusion in a migraine patient
Felix Benninger1, Tal Saban2, Israel Steiner1
1Department of Neurology, Rabin Medical Center, Campus Beilinson, Jabotinsky 39, Petach Tikva 49000, Israel.
Abstract:
We describe a 31-year-old woman with a history of migraines without aura, who presented to our emergency department due to a monocular visual disturbance. This was misdiagnosed as being related to her migraine, however, it was subsequently found to be caused by a central retinal vein occlusion. Patients suffering from migraine can experience visual disturbances in the form of auras. The neuropathological basis for this phenomenon is thought to be a spreading depression in the visual cortex, causing a hemifield active visual phenomenon. Missing the diagnosis of central retinal vein occlusion is common, especially in the setting of an initially normal fundoscopy examination.
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