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Updated: Aug 10, 2026

In vivo Evaluation of Mucociliary Clearance in Mice
Published on: December 18, 2020
Effects of aging on mucociliary clearance
R A Incalzi1, C L Maini, L Fuso
1Department of Geriatrics, Catholic University of the Sacred Heart, Rome, Italy.
Abstract:
Preliminary results from the relationship between aging and mucociliary clearance of inhaled 99-Tc human albumin particles (0.92-2.5 microns) are reported from two groups of healthy non-smokers: 1) 20-61-year-old (mean 42 years) and 2) 71-90-year-old (mean 79.5 years). The analytical procedure is presented, and on the basis of the analysis it is concluded that there is evidence for an age-related decline of the mucociliary clearance by a bi-phasic curve, similar to those reported in the literature for other physiological functions.
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