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[PANCREATIC EXOCRINE INSUFFICIENCY AND ITS CORRECTION IN CHILDREN WITH TYPE I DIABETES IN COMBINATION WITH CELIAC

E V Bolshova, I V Lukashuk, V D Lukashuk

    Likars'Ka Sprava
    |June 30, 2015
    PubMed

    Insights

    Pancreatic exocrine insufficiency (PEN) in children with celiac disease type I was treated with pancreatin. Pancreatin preparations effectively corrected PEN, improving patient outcomes.

    Area of Science:

    • Pediatric Gastroenterology
    • Digestive Health
    • Celiac Disease Research

    Context:

    • Celiac disease, an autoimmune disorder, can lead to secondary pancreatic exocrine insufficiency (PEN) in children.
    • Diagnosis of PEN in pediatric celiac patients requires specific examination.
    • Pancreatic exocrine insufficiency impacts nutrient absorption and overall health.

    Purpose:

    • To evaluate the efficacy of pancreatin preparations in treating pancreatic exocrine insufficiency (PEN) in children diagnosed with celiac disease type I.
    • To assess the therapeutic effect of enzyme replacement therapy on PEN symptoms.

    Summary:

    • Patients with type I celiac disease and diagnosed pancreatic exocrine insufficiency (PEN) were treated with pancreatin.
    • The study examined the effectiveness of pancreatin preparations in correcting PEN.
    • Results indicated a positive therapeutic response to pancreatin treatment.

    Impact:

    • Successful correction of PEN can improve nutritional status and quality of life in children with celiac disease.
    • This study supports the use of pancreatin as a viable treatment for PEN in this pediatric population.
    • Findings contribute to evidence-based management of complications associated with celiac disease.

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