Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Haemostasis in migraine.

E A MacGregor1, H M Chia, C Ridler

  • 1City of London Migraine Clinic.

Cephalalgia : an International Journal of Headache
|December 1, 1989
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Aids to management of headache disorders in primary care (2nd edition) : on behalf of the European Headache Federation and Lifting The Burden: the Global Campaign against Headache.

The journal of headache and pain·2019
Same author

The headache under-response to treatment (HURT) questionnaire, an outcome measure to guide follow-up in primary care: development, psychometric evaluation and assessment of utility.

The journal of headache and pain·2018
Same author

Search for long-lived particles decaying to jet pairs.

The European physical journal. C, Particles and fields·2015
Same author

Observation of two new Ξ(b)(-) baryon resonances.

Physical review letters·2015
Same author

'False' lambda sign in monochorionic twin pregnancy.

Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology·2015
Same author

Measurement of the semileptonic CP asymmetry in B0-B[over ¯]0 mixing.

Physical review letters·2015
Same journal

Rimegepant for migraine prevention in clinical practice: A multicenter study including patients with prior anti-CGRP monoclonal antibody failure (GEMA project).

Cephalalgia : an international journal of headache·2026
Same journal

Cerebrovascular risk with calcitonin gene-related peptide monoclonal antibodies versus onabotulinumtoxinA in patients with migraine: A real-world pharmacoepidemiologic study in the National Institutes of Health All of Us Research Program.

Cephalalgia : an international journal of headache·2026
Same journal

Burning mouth syndrome and oral dysaesthetic/perceptual symptoms: Toward clinically actionable boundaries.

Cephalalgia : an international journal of headache·2026
Same journal

Effectiveness and clinical predictors of rimegepant for acute vertigo in vestibular migraine: A real-world cohort study.

Cephalalgia : an international journal of headache·2026
Same journal

Efficacy of digital therapeutic sinCephalea for personalised nutrition versus control for migraine prevention: A 12-week open-label randomised clinical trial.

Cephalalgia : an international journal of headache·2026
Same journal

SafeTy and effectiveness of Atogepant accoRding to the IHS outcome categories: A multicentric, prospective observational study in real life (the 24-week STAR study).

Cephalalgia : an international journal of headache·2026
See all related articles

Platelets are discussed in migraine pathogenesis. A new Haemostatometer device measured blood clotting in migraineurs between attacks and controls, finding no significant differences in haemostasis, thrombolysis, or coagulation.

Area of Science:

  • Hematology
  • Neurology
  • Vascular Biology

Background:

  • Platelets are implicated in the pathogenesis of migraine.
  • Understanding platelet function in migraine requires precise measurement techniques.

Purpose of the Study:

  • To investigate the role of platelet function in migraine pathogenesis.
  • To compare haemostasis, thrombolysis, and coagulation in migraineurs versus controls using a novel in vitro method.

Main Methods:

  • Utilized a custom-built device, the Haemostatometer, for in vitro analysis.
  • Measured haemostasis, thrombolysis, and coagulation using non-anticoagulated, undiluted (native) blood.
  • Analyzed blood samples from 10 migraineurs (between attacks) and 10 healthy control subjects.

Related Experiment Videos

Main Results:

  • No significant differences were observed in haemostasis between migraineurs and control subjects.
  • Spontaneous thrombolysis showed no difference between the two groups.
  • Coagulation parameters were comparable between migraineurs and control subjects.

Conclusions:

  • The study found no evidence of altered platelet function (haemostasis, thrombolysis, coagulation) in migraineurs between attacks.
  • The Haemostatometer provides a novel method for assessing native blood haemostatic properties.
  • Further research may be needed to explore platelet roles during migraine attacks or in different migraine subtypes.