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Updated: Apr 8, 2026

Detection of Targetable Alterations in Non-small Cell Lung Cancer using Next-generation Sequencing
Published on: October 10, 2025
[Is chemotherapy still an option in oncogene-addicted non-small cell lung cancer? No]
1Service de pneumologie, Hôpital Louis-Pradel, Hospices civils de Lyon 28, avenue du Doyen Lépine, 69677 Lyon cedex, France.
Abstract:
With the emergence of molecular targeted therapies in the management of non-small cell lung cancer, the role of conventional chemotherapy can be questioned. This article presents the key arguments against the use of cytotoxics in presence of a targetable alteration.
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