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Improving Phenotypic Prediction by Combining Genetic and Epigenetic Associations

Sonia Shah1, Marc J Bonder2, Riccardo E Marioni3

  • 1Queensland Brain Institute, University of Queensland, Brisbane 4072, Australia; University of Queensland Diamantina Institute, Translational Research Institute, University of Queensland, Brisbane, QLD 4072, Australia.

American Journal of Human Genetics
|June 30, 2015
PubMed
Summary

DNA methylation profiles explain body mass index (BMI) variation, independent of genetics. Combining genetic and epigenetic data improves BMI prediction, suggesting environmental influences on complex traits.

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