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Extranodal NK/T-cell Lymphoma Mimicking Erythema Multiforme
Ying Xia1, Zhen Yang1, Siyuan Chen1
1Department of Dermatology, Affiliated Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, People's Republic of China.
Abstract:
Extranodal natural killer/T-cell lymphoma (ENKTL) is an extremely rare and an aggressive lymphoma. We report an interesting case of extranodal natural killer/T-cell lymphoma in a middle-aged woman which mimicked erythema multiforme. The skin lesions of this case looked like erythema multiforme due to the tagetoid lesions and mucosal erosions. The two biopsies from her chest and scalp lesions were different. One exhibited the characteristics of CD4+ CD56+ CD8-mycosis fungoides whereas the other biopsy from her scalp showed classical ENKTL histopathological manifestation with positive CD56, cytotoxic proteins and Epstein-Barr virus encoded RNA (EBER).
