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Multiple coronary thrombosis in a patient with thrombocytosis
1Cardiovascular Center, Saiseikai Shimonoseki General Hospital, Yamaguchi, Japan.
Insights
This study reports a case of acute myocardial infarction successfully treated with urokinase. The patient also had thrombocytosis, prompting a discussion on its relationship with myocardial infarction.
Area of Science:
- Cardiology
- Hematology
Background:
- Acute myocardial infarction (AMI) necessitates prompt reperfusion therapy.
- Coronary artery occlusion, often due to thrombus, is the primary cause of AMI.
Observation:
- A 59-year-old female presented with acute inferior myocardial infarction.
- Cardiac catheterization identified complete occlusion of the right coronary artery and a thrombus in the left anterior descending artery.
Findings:
- Simultaneous intracoronary urokinase infusion successfully recanalized the right coronary artery.
- The left anterior descending artery thrombus was successfully lysed and dispersed distally.
- Laboratory tests revealed thrombocytosis in the patient.
Implications:
- This case highlights the efficacy of intracoronary urokinase in managing complex coronary artery occlusions.
- The presence of thrombocytosis warrants further investigation into its association with myocardial infarction.
- Understanding the interplay between thrombocytosis and myocardial infarction may inform future treatment strategies.
Abstract:
A 59-year-old woman was admitted with acute inferior myocardial infarction. Cardiac catheterization revealed total occlusion in the right coronary artery and thrombus-like filling defect in the left anterior descending coronary artery. With simultaneous intracoronary urokinase infusion to the right and left coronary arteries, the right coronary artery became patent and the thrombus in the left anterior descending coronary artery was released to the distal coronary artery. Thrombocytosis was disclosed by laboratory examination. The relationship between myocardial infarction and thrombocytosis is discussed.