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How common is diabetic nephropathy?

¹Arrowe Park Hospital, Wirral, Merseyside, UK.

Diabetes Research (Edinburgh, Scotland)

|April 1, 1989

Summary

This summary is machine-generated.

Diabetic nephropathy prevalence is lower than expected, with only 2.1% of patients showing definite signs. Early kidney damage may impact survival rates before established diabetic nephropathy develops.

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Area of Science:

Nephrology
Endocrinology
Diabetology

Background:

Diabetic nephropathy is a major complication of diabetes mellitus.
Previous estimates suggest a higher prevalence of overt nephropathy.

Purpose of the Study:

To determine the prevalence of definite diabetic nephropathy in a diabetic clinic population.
To investigate potential reasons for lower-than-expected prevalence.

Main Methods:

A retrospective study of 1,356 diabetic patients over 12 months.
Application of strict diagnostic criteria for definite diabetic nephropathy.

Main Results:

Only 28 patients (2.1%) met the criteria for definite diabetic nephropathy.
The observed prevalence is lower than previously reported figures.

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Conclusions:

The prevalence of overt diabetic nephropathy may be overestimated in prior reports.
High mortality in patients with early kidney damage (microalbuminuria/proteinuria) might explain the lower observed prevalence of established disease.