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Published on: August 25, 2014
Perinatal dioxin exposure and psychosocial and behavioral development in school-aged children
Yumi Kono1, Akira Oka2, Hiroshi Tada3
1Department of Pediatrics, Jichi Medical University, 3311-1 Yakushiji, Shimotsuke-shi, Tochigi 329-0498, Japan.
Insights
This study found no link between dioxin exposure from breastfeeding and behavioral issues in children. These findings support the recommendation of breastfeeding for infant health.
Area of Science:
- Environmental Health
- Pediatrics
- Toxicology
Background:
- Perinatal exposure to environmental contaminants like dioxins is a public health concern.
- Breastfeeding is crucial for infant development, but potential risks from contaminant transfer require investigation.
Purpose of the Study:
- To examine the association between dioxin levels in breast milk and children's behavioral and psychosocial problems.
- To determine if estimated dioxin exposure (EDE) through breastfeeding correlates with behavioral outcomes in Japanese children.
Main Methods:
- Dioxin levels in breast milk and breastfeeding duration were used to calculate EDE for infants born 1998-2005.
- Mothers of 175 children completed the Japanese Social Difficulties Questionnaire (SDQ) when children were 6-13 years old.
- Statistical analyses, including linear multiple regression, adjusted for potential confounding factors.
Main Results:
- No significant correlation was found between breast milk dioxin levels and the total difficulties score (TDS) on the SDQ for either boys or girls.
- Estimated dioxin exposure (EDE) did not correlate with the TDS in either sex.
- Mean dioxin levels and EDEs were reported for boys and girls.
Conclusions:
- The study found no evidence of a link between perinatal dioxin exposure and behavioral or psychosocial problems in children.
- These results reinforce the established benefits of breastfeeding for infant well-being.
- Further research may explore other environmental factors or developmental outcomes.
Objective:
The aim of this study was to elucidate the association between psychosocial and behavioral problems in children at school age and dioxin level in breast milk or estimated dioxin exposure (EDE) through breastfeeding in the general Japanese population.
Methods:
Dioxin level of breast milk at 1month of age and breastfeeding ratio through the first year of life were used to calculate the EDE of infants born in 1998-2005 in Japan. The Japanese Social Difficulties Questionnaire (SDQ) for the assessment of children's behavior was sent by mail to mothers whose breast milk underwent the dioxin survey, at the time when their infants were aged 6-13 years.
Results:
The study subjects were 175 pairs of mothers and their first infants (79 boys, 96 girls). The mean total dioxin levels of breast milk were 18.3 and 19.8 (pgTEQ/g fat) and EDEs were 16.4 and 19.6 (ngTEQ/kg/year) in boys and girls, respectively. In linear multiple regression analyses after adjusting for age at SDQ, maternal age, birth weight and maternal smoking habit, dioxin level in breast milk was not significantly related to the total difficulties score (TDS) of SDQ in boys, B=2.29 (95% CI -7.60-12.18), or in girls, B=-1.04 (95% CI -9.24-7.15). EDE correlated to the TDS in neither boys, B=-0.99 (95% CI -4.14-2.15), nor girls, B=1.08 (95% CI -2.69-4.85).
Conclusion:
No evidence was found of a correlation between perinatal dioxin exposure and behavioral and psychosocial problems of children measured by SDQ. These results support the benefits of recommending breastfeeding.
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