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Atomic Absorbance Spectroscopy to Measure Intracellular Zinc Pools in Mammalian Cells
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Modeling Zinc Intake for Intervention and Scenario Analysis.

Nazanin Abbaspour1, Manouchehr Amini2, Richard Hurrell2

  • 1ETH Zurich, Institute of Terrestrial Ecosystems, Zurich, Switzerland naz.abbaspour@yahoo.com.

Food and Nutrition Bulletin
|June 30, 2015
PubMed
Summary

Zinc deficiency affects one-third of the global population. Modeling shows wheat fortification and biofortification are effective strategies to combat this widespread issue within 15 years.

Keywords:
biofortificationfood consumptionphytic acidzinc deficiency

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Area of Science:

  • Nutritional Science
  • Public Health
  • Agricultural Science

Background:

  • Zinc deficiency is a significant global health problem, impacting one-third of the world's population.
  • Inadequate intake of bioavailable zinc is the primary cause, particularly prevalent in developing countries within arid regions.

Purpose of the Study:

  • To utilize a modeling approach to evaluate dietary scenarios for eliminating zinc deficiency in a test population.
  • To analyze the effectiveness of different interventions in addressing widespread zinc deficiency.

Main Methods:

  • Developed a comprehensive database on food consumption patterns and zinc/phytic acid content for two Iranian population groups.
  • Constructed and parameterized a zinc intake model, incorporating bioavailability and uncertainties.
  • Employed scenario analyses to predict the impact of dietary changes on zinc intake.

Main Results:

  • Approximately one-third of both study populations had zinc intake below the Estimated Average Requirement (EAR).
  • Current dietary patterns would require 60 years to meet zinc EARs for 97.5% of the population.
  • Wheat flour fortification and biofortification predicted to help 93% and 88% of the population meet EARs within 15 years, respectively.

Conclusions:

  • Modeled results indicate that food fortification and biofortification are highly effective and sustainable strategies against zinc deficiency.
  • The developed modeling methodology is versatile and valuable for analyzing future trends and intervention effectiveness.