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Impact of System Factors and Modifiable ICU Interventions on the Outcome of Cardio-pulmonary Resuscitation in PICU
1Department of Pediatric Intensive Care Unit, the First Affiliated Hospital of Sun Yat-sen University, China. Correspondence to: Wen Tang Zhongshan second Road, Guangzhou 510080, PR, China. tangwenr@21cn.com.
Insights
System factors did not impact pediatric cardiac arrest survival in this PICU. However, pre-arrest sedation may improve outcomes for pediatric patients experiencing cardiac arrest.
Area of Science:
- Pediatric Critical Care Medicine
- Cardiology
- Resuscitation Science
Background:
- Cardiac arrest outcomes in pediatric intensive care units (PICUs) are influenced by various factors.
- Understanding system and modifiable factors is crucial for improving resuscitation success rates in critically ill children.
Purpose of the Study:
- To evaluate the influence of system-related elements and adjustable interventions on the success of cardiac arrest resuscitation within a pediatric intensive care unit.
- To identify key factors affecting immediate outcomes following cardiac arrest in pediatric patients.
Main Methods:
- A retrospective analysis of medical records was conducted.
- The study included children under 14 years old who experienced cardiac arrest in a Chinese hospital's PICU over two years.
Main Results:
- Out of 94 cardiac arrest events, 61 achieved successful resuscitation.
- No significant association was found between personal or unit factors and immediate resuscitation outcomes.
- Unsuccessful resuscitation rates were lower in sedated patients (26%) compared to non-sedated (50%), and in those on positive pressure ventilation (19%) versus those not (74%).
- Resuscitation attempts exceeding 30 minutes significantly increased the odds of unsuccessful outcomes (135-fold).
- Patients receiving base supplementation had a higher rate of unsuccessful resuscitation (78%) than those who did not (21%).
Conclusions:
- System factors did not demonstrate a significant impact on the outcomes of cardiopulmonary resuscitation in this PICU.
- Pre-arrest sedation in critically ill pediatric patients may be associated with improved outcomes following cardiac arrest.
Objective:
To assess the impact of system factors and modifiable interventions on outcome of cardiac arrest in a pediatric intensive care unit.
Design:
Retrospective medical record review.
Setting:
Pediatric intensive care unit of a hospital in China.
Participants:
Children (age<14 yrs) who had cardiac arrest within our PICU over a period of two years.
Results:
Sixty-one of the 94 cardiac arrest events were successfully resuscitated. There was no significant association between personal and unit factors with immediate outcomes in our unit. The rate of unsuccessful resuscitation in sedated patients and those without sedation was 26% and 50%, respectively. Unsuccessful resuscitation occurred in 19% of patients who were on positive pressure ventilation as compared with 74% for those without positive pressure ventilation. Arrests which had resuscitation attempts that lasted more than 30 min had 135-fold higher odds of unsuccessful outcome. 78% of patients who received base supplement at the time of arrest had unsuccessful resuscitation compared with 21% for those without base supplement.
Conclusion:
Our data shows no impact of system factors on the outcome of cardio-pulmonary resuscitation in our PICU. Pre-arrest sedation in pediatric critical ill patients might be beneficial to the outcome of cardiac arrests.
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