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Related Concept Videos

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Anaphylaxis is a severe, life-threatening hypersensitivity reaction mediated by Immunoglobulin E (IgE) antibodies. When IgE binds to allergens, it triggers the release of mediators– histamine, leukotrienes, and prostaglandins from mast cells and basophils. These mediators cause vasodilation, edema, and inflammation, leading to various symptoms.The primary allergens causing anaphylaxis include food items (e.g., peanuts, shellfish), drugs (e.g., penicillin, asparaginase, corticotropin,...
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Intravenous anesthetics are drugs administered parenterally to induce anesthesia or sedation. Propofol is a widely used agent formulated as a 1% emulsion in soybean oil, glycerol, and egg phosphatide. It induces rapid anesthesia primarily due to its rapid distribution from the bloodstream to target tissues and is metabolized in the liver. However, it can cause significant pain on injection and hypertriglyceridemia. Fospropofol, a water-based prodrug of propofol, lacks these adverse effects.
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Vigilant monitoring for aneurysm rupture is essential for patients undergoing aortic surgery.Preoperative Nursing ManagementContinuously monitor the patient for manifestations of aneurysm rupture, such as pallor, weakness, tachycardia, hypotension, abdominal, back, groin, or periumbilical pain, changes in consciousness, and a pulsating abdominal mass. Regularly assess the patient's peripheral pulses.Instruct the patient to consume a clear liquid diet the day before surgery and administer...
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Updated: Apr 8, 2026

Percutaneous Hepatic Perfusion PHP with Melphalan as a Treatment for Unresectable Metastases Confined to the Liver
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Perioperative anaphylaxis.

Marta Inés Berrío Valencia1

  • 1Hospital Pablo Tobón Uribe, Medellín, Colombia.

Brazilian Journal of Anesthesiology (Elsevier)
|July 1, 2015
PubMed
Summary
This summary is machine-generated.

Perioperative anaphylaxis is a rare but serious cause of surgical death. Early diagnosis and prompt treatment with adrenaline are crucial for patient survival.

Keywords:
AnafilaxiaAnaphylaxisAnestesiaAnesthesiaHipersensibilidadeHypersensitivityPerioperative periodPeríodo perioperatórioTerapêuticaTreatment

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Area of Science:

  • Anesthesiology
  • Immunology

Background:

  • Anaphylaxis is a critical cause of perioperative mortality.
  • It is often unexpected and rapidly escalates to a life-threatening condition.

Purpose of the Study:

  • To review the diagnosis and management of perioperative anaphylaxis.
  • To highlight the importance of anesthesiologist awareness.

Main Methods:

  • Narrative review of perioperative anaphylaxis.

Main Results:

  • Diagnostic tests aid in preventing recurrent events.
  • Adrenaline and intravenous fluids are primary treatments.

Conclusions:

  • Anesthesiologists must be proficient in diagnosing, managing, and monitoring anaphylaxis.
  • Familiarity with perioperative anaphylaxis protocols is essential.