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Vascular contributions to cognitive impairment.
Clinton B Wright1, Alan Flores1
1Evelyn F. McKnight Brain Institute and the Departments of Neurology, Public Health Sciences, and the Neuroscience Program (CBW), Leonard M. Miller School of Medicine, University of Miami, FL; and Department of Neurology, Vall d'Hebron University Hospital, Vall d'Hebron Research Institute and Department of Medicine (AF), Universitat Autonoma de Barcelona, Barcelona, Spain.
Vascular cognitive impairment (VCI) is preventable, unlike many neurodegenerative dementias. Early physician vigilance and education are crucial for managing VCI, offering hope for limiting its progression.
Area of Science:
- Neurology
- Geriatrics
- Public Health
Background:
- Vascular cognitive impairment (VCI) presents heterogeneously and is complex.
- Unlike neurodegenerative causes, vascular damage is preventable.
- Physician education and vigilance are vital for VCI management.
Purpose of the Study:
- To outline an approach for diagnosing patients with possible VCI.
- To summarize current guidelines for VCI treatment and prevention.
- To provide an overview of VCI with illustrative case examples.
Main Methods:
- Literature review of VCI.
- Synthesis of current treatment and prevention guidelines.
- Case study analysis.
Main Results:
- VCI is a significant cause of cognitive impairment.
- Preventable vascular damage underlies VCI.
- A structured approach to VCI diagnosis and management is feasible.
Conclusions:
- Early identification and intervention can alter the course of VCI.
- Physician education on VCI is essential for improving patient outcomes.
- Preventive strategies hold significant potential for reducing VCI prevalence.
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