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Frequent relapser minimal change nephrosis: an unrecognized X-linked disorder?
N B Awadalla1, A S Teebi, A Y Elzouki
1Department of Paediatrics, Amiri Hospital and Faculty of Medicine, Raas, Kuwait.
European Journal of Pediatrics
|December 1, 1989
Abstract:
We report three brothers who developed nephrosis between the age of 3-10 years. The parents were nonconsanguineous and of Arab descent. The mother's sister had a son with a similar condition. Patients were steroid responders and frequent relapsers. Renal biopsies in the three brothers showed findings of minimal change nephrosis. This family may suggest the existence of an X-linked recessive nephrosis which provides further evidence for genetic heterogeneity of familial nephrosis.