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Blood concentrations after accidental cyclosporin overdose
K de Meer1, R H Houwen, C M Bijleveld
1Department of Paediatrics, University Hospital Groningen, The Netherlands.
European Journal of Pediatrics
|December 1, 1989
Abstract:
Two cases of children are reported with an accidental oral overdose of cyclosporin in whom blood concentrations were monitored. Despite a tenfold oral overdose, the peak blood concentrations of cyclosporin in both patients were only moderately increased above therapeutic levels. Apart from a transient rise in blood pressure in one patient, no toxic effects of cyclosporin were noticed.