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Protein Dynamics in Living Cells

Protein Dynamics in Living Cells

Different fluorescence-based techniques are used to study the protein dynamics in living cells. These techniques include FRAP, FRET, and PET.
Fluorescent recovery after photobleaching (FRAP) is a fluorescent-protein-based detection technique used to quantify protein movement rates within the cell. This method exposes a small portion of the cell to an intense laser beam. The laser beam causes permanent photobleaching of the fluorophore-tagged proteins in the exposed region. As the bleached...

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Updated: Apr 8, 2026

Using Three-color Single-molecule FRET to Study the Correlation of Protein Interactions

Using Three-color Single-molecule FRET to Study the Correlation of Protein Interactions

Published on: January 30, 2018

InferenceMAP: mapping of single-molecule dynamics with Bayesian inference

Mohamed El Beheiry¹, Maxime Dahan¹, Jean-Baptiste Masson²

¹1] Physico-Chimie Curie, Institut Curie, Paris Sciences Lettres, CNRS UMR 168, Université Pierre et Marie Curie-Paris 6, Paris, France. [2] Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, Virginia, USA.

|July 1, 2015

Summary

No abstract available in PubMed .

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