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Effects of the novel compound, Hoe 065, upon impaired learning and memory in rodents
F J Hock1, H J Gerhards, G Wiemer
1Hoechst AG, Frankfurt/M., F.R.G.
European Journal of Pharmacology
|November 14, 1989
Abstract:
The effects of Hoe 065 (n-octyl 2-[N-[(S)-1-ethoxycarbonyl-3-phenylpropyl]-L-alanyl]-(1S,3S, 5S)-2-azabicyclo [3.3.0]octane-3-carboxylate maleate salt) were studied on the performance of mice and rats in different learning tasks. Hoe 065 prevented the disruption of memory induced by scopolamine administered before training. The results indicate that Hoe 065 improves cognitive function in different tasks.