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Updated: Apr 8, 2026

Induction of Drug-Induced, Autoimmune Hepatitis in BALB/c Mice for the Study of Its Pathogenic Mechanisms
Published on: May 29, 2020
A Case Report of Supplement-Induced Hepatitis in an Active Duty Service Member
Michael J Brazeau1, Joni L Castaneda1, Sonny S Huitron1
1Department of Gastroenterology, William Beaumont Army Medical Center, 5005 North Piedras St. El Paso, TX 79920.
Abstract:
The incidence of drug-induced hepatic injury has been increasing as a result of more widespread use of workout supplements containing anabolic steroids to increase muscle mass. Synthetic androgenic steroids are shown to cause cholestatic liver injury, but the exact mechanism of injury is not completely understood. We present a case of a healthy, young, active duty Army male soldier who developed pruritis and jaundice shortly after starting to take a body-building supplement containing anabolic steroids, and was subsequently found to have significant biopsy proven drug-induced liver injury.

