Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Typical Model Studies

Typical Model Studies

Fluid mechanics model studies often utilize scaled-down systems to predict fluid behavior in full-scale environments, such as river flows, dam spillways, and structures interacting with open surfaces. Maintaining Froude number similarity in river models is crucial, as it replicates surface flow features like wave patterns and velocities.

Steady, Laminar Flow in Circular Tubes

Steady, Laminar Flow in Circular Tubes

Hagen-Poiseuille flow describes a viscous fluid's steady, incompressible flow through a cylindrical tube with a constant radius R. This flow profile is often applied to understand fluid transport in narrow channels, such as capillaries. It serves as a foundational example of laminar flow. In this model, cylindrical coordinates (r,θ,z) are used to describe the radial (r), angular (θ), and axial (z) dimensions within the tube. For Hagen-Poiseuille flow, the velocity profile is purely axial,...

Bioreactor Controls-II

Bioreactor Controls-II

In aerobic fermentations, oxygen is vital for microbial growth and metabolite production. Since air comprises only about 20% oxygen and the gas is poorly soluble in water—just 9 ppm at 20°C—supplying sufficient oxygen becomes a critical challenge, especially in high-demand processes like yeast growth or citric acid production. Even a fully saturated broth may offer only a few seconds of oxygen availability.To address this, sterile or scrubbed air is introduced into the...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Pathway-Aware Template-Based Retrosynthesis.

Journal of chemical information and modeling·2026

Same author

Machine Learning and Autonomous Systems for Accelerated Synthesis.

Annual review of analytical chemistry (Palo Alto, Calif.)·2026

Same author

Data-driven recommendation of agents, temperature, and equivalence ratios for organic synthesis.

Chemical science·2025

Same author

General Chemically Intuitive Atom- and Bond-Level DFT Descriptors for Machine Learning Approaches to Reaction Condition Prediction.

Journal of chemical information and modeling·2025

Same author

Developing Pharmaceutically Relevant Pd-Catalyzed C-N Coupling Reactivity Models Leveraging High-Throughput Experimentation.

Journal of the American Chemical Society·2025

Same author

ASKCOS: Open-Source, Data-Driven Synthesis Planning.

Accounts of chemical research·2025

Same journal

Microfluidic rare cell analysis beyond counting: workflow design from enrichment to multi-omics.

Lab on a chip·2026

Same journal

A sperm racetrack to separate sperm by swim speed.

Lab on a chip·2026

Same journal

Controlled encapsulation and droplet size prediction in two-step microfluidic double emulsions.

Lab on a chip·2026

Same journal

A particulate blood-mimicking fluid with physiological biconcave geometry for microscale hemorheology.

Lab on a chip·2026

Same journal

Multicellular sensor arrays fabricated by capillary stamping for pattern-based odor discrimination.

Lab on a chip·2026

Same journal

A real-time microfluidic surveillance system for multiplex detection of heavy metal contamination in wastewater.

Lab on a chip·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Apr 8, 2026

Analyzing Mixing Inhomogeneity in a Microfluidic Device by Microscale Schlieren Technique

Analyzing Mixing Inhomogeneity in a Microfluidic Device by Microscale Schlieren Technique

Published on: June 12, 2015

Characterization and modeling of multiphase flow in structured microreactors: a post microreactor case study.

Lu Yang¹, Yanxiang Shi, Milad Abolhasani

¹Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA. kfjensen@mit.edu.

|July 2, 2015

Summary

This summary is machine-generated.

Structured microreactors with internal posts enhance mass transfer. Laser-induced fluorescence and CFD simulations quantify flow fields and interfacial area, revealing improved performance over open channels.

More Related Videos

Microfluidic Fabrication Techniques for High-Pressure Testing of Microscale Supercritical CO2 Foam Transport in Fractured Unconventional Reservoirs

Microfluidic Fabrication Techniques for High-Pressure Testing of Microscale Supercritical CO2 Foam Transport in Fractured Unconventional Reservoirs

Published on: July 2, 2020

Multi-Stream Perfusion Bioreactor Integrated with Outlet Fractionation for Dynamic Cell Culture

Multi-Stream Perfusion Bioreactor Integrated with Outlet Fractionation for Dynamic Cell Culture

Published on: July 20, 2022

Related Experiment Videos

Last Updated: Apr 8, 2026

Analyzing Mixing Inhomogeneity in a Microfluidic Device by Microscale Schlieren Technique

Analyzing Mixing Inhomogeneity in a Microfluidic Device by Microscale Schlieren Technique

Published on: June 12, 2015

Microfluidic Fabrication Techniques for High-Pressure Testing of Microscale Supercritical CO2 Foam Transport in Fractured Unconventional Reservoirs

Microfluidic Fabrication Techniques for High-Pressure Testing of Microscale Supercritical CO2 Foam Transport in Fractured Unconventional Reservoirs

Published on: July 2, 2020

Multi-Stream Perfusion Bioreactor Integrated with Outlet Fractionation for Dynamic Cell Culture

Multi-Stream Perfusion Bioreactor Integrated with Outlet Fractionation for Dynamic Cell Culture

Published on: July 20, 2022

Area of Science:

Chemical Engineering
Fluid Dynamics
Microfluidics

Background:

Microreactors offer enhanced control over chemical processes.
Structured internals, like posts, can significantly alter flow behavior and mass transfer.
Understanding these effects is crucial for optimizing microreactor design.

Purpose of the Study:

To investigate flow fields and mass transfer in microreactors with internal posts.
To quantify the impact of posts on interfacial area and phase holdup.
To compare the performance of structured microreactors with open channels.

Main Methods:

Laser-induced fluorescence (LIF) visualization for flow field analysis.
Image analysis to quantify interfacial area, phase holdup, and wetting layer characteristics.
Computational fluid dynamics (CFD) simulations using the volume-of-fluid (VOF) method.

Main Results:

Systematic quantification of key interfacial and wetting layer parameters.
Demonstration of enhanced mass transfer in post-structured microreactors compared to open channels.
CFD simulations showed good agreement with experimental flow observations.

Conclusions:

Internal posts significantly enhance mass transfer performance in microreactors.
The study provides a quantitative understanding of post-induced flow modifications.
Predictions for mass transfer performance under various conditions are established.