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Synthesis and Structure Determination of µ-Conotoxin PIIIA Isomers with Different Disulfide Connectivities
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Disulfide Bridges in Defensins

Bing-Chuan Zhao, Hua-Can Lin, Dan Yang

  • 1Department of Chemical Biology and Biotechnology, Peking University Shenzhen Graduate School, Shenzhen University Town, Lishui Road, Xili, Nanshan District, Shenzhen, 518055, P. R. China. lizg@pkusz.edu.cn.

Current Topics in Medicinal Chemistry
|July 2, 2015
PubMed
Summary

Defensins are antimicrobial peptides crucial for immunity. This review explores how their disulfide bonds influence antimicrobial activity and potential pharmaceutical uses.

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