[Photodynamic therapy of psoriasis palmaris et plantaris using a topically applied hematoporphyrin derivative and...

Two different hematoporphyrin derivative (HpD) containing ointments were checked for their photodynamic efficacy in 17 patients suffering from palmoplantar psoriasis. Following topical application and subsequent irradiation with visible light, in all the patients psoriatic plaques resolved either to some substantial degree or totally. That method of treatment so far is recommendable for treating psoriasis of markedly hornifyed skin regions. However, further efforts are needed to perfect therapeutical circumstances like preparation time, spectral distribution of light and galenics of HpD-containing ointment.