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Correlation between serum cystatin C level and elderly hypertensive patients combined coronary heart disease

Ying Wang1, Xianming Su2, Wei Zhang2

  • 1The Medicine School of Xi'an Jiaotong University Xi'an 710061, Shaanxi ; Department of Geriatric Cardiology, The Nuclear Industry 215 Hospital Xianyang 712000, Shaanxi.

International Journal of Clinical and Experimental Medicine
|July 2, 2015
PubMed

Insights

Serum cystatin C levels correlate with blood pressure and coronary artery stenosis severity in elderly patients. Higher levels indicate more severe hypertension and coronary heart disease, suggesting cystatin C as a potential disease severity predictor.

Area of Science:

  • Cardiology
  • Nephrology
  • Geriatrics

Background:

  • Elderly hypertension and coronary heart disease (CHD) are significant health concerns.
  • Biomarkers are needed to assess disease severity in these patients.

Purpose of the Study:

  • To investigate the relationship between serum cystatin C levels and elderly patients with both hypertension and CHD.
  • To determine if serum cystatin C can predict disease severity.

Main Methods:

  • Serum cystatin C levels were measured in 500 patients with hypertension and CHD using immunoturbidimetry.
  • Correlations were analyzed between cystatin C levels, blood pressure, and coronary artery stenosis degree.

Main Results:

  • Serum cystatin C levels showed a strong positive correlation with both blood pressure and coronary artery stenosis severity.
  • Patients with both hypertension and CHD had significantly higher cystatin C levels compared to control groups.

Conclusions:

  • Serum cystatin C levels are closely linked to the severity of hypertension and coronary artery stenosis in elderly patients.
  • Serum cystatin C may serve as a valuable predictor for disease severity in elderly patients with hypertension and CHD.
Abstract

Keywords:
Cystatin Ccoronary artery diseasecorrelationelderly patientshypertension

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