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Updated: Apr 7, 2026

In Vivo Functional Study of Disease-associated Rare Human Variants Using Drosophila
Published on: August 20, 2019
Syndrome in Question
Nilton Di Chiacchio1, Julio Cesar Jasso-Olivares2, Nilton Gioia Di Chiacchio1
1Hospital do Servidor Público Municipal, São Paulo, SP, Brazil.
Abstract:
The Iso-Kikuchi Syndrome is a rare condition characterized by nail dysplasia involving the index fingers, including micronychia, polyonychia, anonychia, irregular lunula, malalignment and hemionychogryphosis. On the antero-posterior image, radiologic examination reveals a narrowing of the distal phalanx. The lateral image shows a Y-shaped bifurcation of the distal phalanx. We report a case of a patient with typical clinical and radiologic signs of Iso-Kikuchi Syndrome.
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