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The most common cardiovascular diagnostic test is an X-ray. It produces images of the heart, blood vessels, and adjacent structures.
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Updated: Apr 7, 2026

Voluntary Breath-hold Technique for Reducing Heart Dose in Left Breast Radiotherapy
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Cardiac Side-effects From Breast Cancer Radiotherapy.

C W Taylor1, A M Kirby2

  • 1Clinical Trial Service Unit, Richard Doll Building, Oxford, UK.

Clinical Oncology (Royal College of Radiologists (Great Britain))
|July 3, 2015
PubMed
Summary
This summary is machine-generated.

Radiotherapy for breast cancer can increase heart disease risk. Oncologists estimate individual risks based on cardiac radiation dose and patient history to balance treatment benefits against potential harm.

Keywords:
Breast cancer radiotherapycardiac-sparing breast radiotherapylong-term effectsradiation-related heart disease

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Area of Science:

  • Oncology
  • Radiotherapy
  • Cardiology

Background:

  • Breast cancer radiotherapy significantly reduces recurrence and mortality.
  • Radiotherapy can lead to radiation exposure of the heart, increasing the risk of heart disease.
  • Individualized risk assessment is crucial for balancing treatment benefits and cardiac risks.

Purpose of the Study:

  • To estimate the absolute risks of radiation-related heart disease in breast cancer patients.
  • To inform oncologists in planning personalized radiotherapy treatments.
  • To compare the absolute benefit of radiotherapy with the estimated cardiac risks.

Main Methods:

  • Review of randomized trials to analyze heart disease risks.
  • Estimation of individual cardiac radiation doses.
  • Assessment of patients' background risk of ischemic heart disease.
  • Evaluation of technical approaches to minimize heart dose.

Main Results:

  • Many UK centers currently achieve mean heart doses below 3 Gy.
  • For most women, radiotherapy benefits likely outweigh cardiac risks.
  • Technical strategies like breath-holding and proton therapy are employed to reduce heart dose.

Conclusions:

  • Personalized risk-benefit analysis is essential for breast cancer radiotherapy.
  • Minimizing cardiac radiation dose is a key focus in treatment planning.
  • Advanced techniques are being developed to further reduce heart exposure during radiotherapy.