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Updated: Apr 7, 2026

Quantitative Magnetic Resonance Imaging of Skeletal Muscle Disease
Published on: December 18, 2016
Single-frequency excitation wideband MRI (SE-WMRI)
Edzer L Wu1, Yun-An Huang2, Tzi-Dar Chiueh3
1Institute of Biomedical Engineering, National Taiwan University, Taipei 106, Taiwan and MRI/MRS Interdisciplinary Laboratory, National Taiwan University, Taipei 106, Taiwan.
Purpose:
In this study, single-frequency excitation wideband magnetic resonance imaging (MRI) (SE-WMRI) was proposed to obtain high-quality accelerated images by reducing phase-encoding steps while applying separation gradients.
Methods:
A zig-zag k-space trajectory with reduced phase-encoding steps and an increased readout sampling rate was proposed. A unique gradient design with buffer intervals near the trajectory turns was employed to avoid undersampling and image artifacts. A gridding method and Fourier transform were used for image reconstruction. Quantitative analysis was performed on phantom images to investigate the characteristics of the acceleration method.
Results:
The proposed method showed evident improvements in the accelerated phantom images, substantially reducing the ringing and blurring artifacts found using previous methods. Furthermore, the accelerated images exhibited the same signal-to-noise ratio as standard imaging. The accelerated in vivo experiment also produced the same quality as standard imaging.
Conclusions:
The proposed SE-WMRI method can effectively remove image artifacts and acquire images of higher temporal or spatial resolutions with less compromise.
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